2026

1. Hu R, Park J, Qian Y, Xiong S, Elsabbagh AH, Chhikara A, Fan H, Shi Z, Liu L, Li Y, Song Z, Mahmoud AM, Chen J, Baur JA, He Y, Layden BT, Zhou Z, Xu P, Ong SG, Wang Z, Jiang Y. ERalpha activates NAMPT/IL-33 signaling to enhance beige thermogenesis and metabolic fitness. Sci Adv. 2026;12(2):eadz1385. Epub 2026/01/07. doi: 10.1126/sciadv.adz1385. PubMed PMID: 41499496; PMCID: PMC12778055.
2. Xu G, Zhou J, Xu P, Gyawali I, Xu C, Yang J, Ma Z, Du D, Jiang Q, Shu G. Alpha‐Ketoglutarate Regulates Intestinal Motility and Health by OXGR1 in Nitrergic Neuron of Enteric Nervous System. Food Front. 2026;7(1). Epub 2026/01/09. doi: https://doi.org/10.1002/fft2.70216.
3. Li R, Liu M, Zhang Z, Zhu Q, Chen M, Liu J, Pan L, Su A, Zhou Q, Qi R, Liu Z, Wu R, Wang S, Wang L, Shu G, Xu P, Jiang Q, Zhu C. High ambient temperature activates a neural circuit for gut glucose uptake in male mice. Nat. Commun. 2026. Epub 2026/07/15. doi: 10.1038/s41467-026-75522-7. PubMed PMID: 42448680.
4. Beverley K, Munoz M, Ahn S, Granados S, Master E, Phillips S, Fancher I, Xu P, Levitan I. Protection against diet-induced weight gain by a single-point mutation in Kir2.1 channels. Sci. Rep. (in press)
5. Zhao Q, Feng B, Dong V, Lau L, Liu H, Yu M, Liang K, Tran C, Feng H, Smiley T, Gao P, Yan A, Ye H, Jiang Y, Wang C, Xu P, He Y. Serotonin neurons in the dorsal raphe control food craving-like behavior during pregnancy in mice. Nat. Neurosci. (in press)

2025

1. Yu M, Feng B, Bean JC, Zhao Q, Yang Y, Liu H, Li Y, Eappen BP, Liu H, Tu L, Conde KM, Wang M, Chen X, Yin N, Threat DA, Xu N, Han J, Gao P, Zhu Y, Hadsell DL, He Y, Xu P, He Y, Wang C. Suppression of hypothalamic oestrogenic signal sustains hyperprolactinemia and metabolic adaptation in lactating mice. Nat Metab. 2025. Epub 2025/04/11. doi: 10.1038/s42255-025-01268-z. PubMed PMID: 40211044.
2. Zhang N, Yu M, Zhao Q, Feng B, Deng Y, Bean JC, Liu Q, Eappen BP, He Y, Conde KM, Liu H, Yang Y, Tu L, Wang M, Li Y, Yin N, Liu H, Han J, Threat DA, Xu N, Smiley T, Xu P, Chen L, Zeng T, He Y, Wang C. Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females. Mol Metab. 2025;93:102108. Epub 2025/02/06. doi: 10.1016/j.molmet.2025.102108. PubMed PMID: 39909189.

2024

1. Yuan Y, Hu R, Park J, Xiong S, Wang Z, Qian Y, Shi Z, Wu R, Han Z, Ong SG, Lin S, Varady KA, Xu P, Berry DC, Shu G, Jiang Y. Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure. Sci Adv. 2024;10(26):eadn5229. Epub 2024/06/26. doi: 10.1126/sciadv.adn5229. PubMed PMID: 38924414; PMCID: PMC11204298.
2. Ye H, Yang X, Feng B, Luo P, Torres Irizarry VC, Carrillo-Saenz L, Yu M, Yang Y, Eappen BP, Munoz MD, Patel N, Schaul S, Ibrahimi L, Lai P, Qi X, Zhou Y, Kota M, Dixit D, Mun M, Liew CW, Jiang Y, Wang C, He Y, Xu P. 27-Hydroxycholesterol acts on estrogen receptor alpha expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior. Sci Adv. 2024;10(28):eadi4746. Epub 2024/07/12. doi: 10.1126/sciadv.adi4746. PubMed PMID: 38996023; PMCID: PMC11244552.
3. Torres Irizarry VC, Feng B, Yang X, Patel N, Schaul S, Ibrahimi L, Ye H, Luo P, Carrillo-Saenz L, Lai P, Kota M, Dixit D, Wang C, Lasek AW, He Y, Xu P. Estrogen signaling in the dorsal raphe regulates binge-like drinking in mice. Transl Psychiatry. 2024;14(1):122. Epub 2024/02/28. doi: 10.1038/s41398-024-02821-2. PubMed PMID: 38413577; PMCID: PMC10899193.
4. Park J, Hu R, Qian Y, Xiong S, El-Sabbagh AS, Ibrahim M, Wang J, Xu Z, Chen Z, Song Q, Song Z, Yan G, Mahmoud AM, He Y, Layden BT, Chen J, Ong SG, Xu P, Jiang Y. Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response. Nat Aging. 2024;4(6):839-53. Epub 2024/06/11. doi: 10.1038/s43587-024-00633-z. PubMed PMID: 38858606.

2023

1. Wu R, Park J, Qian Y, Shi Z, Hu R, Yuan Y, Xiong S, Wang Z, Yan G, Ong SG, Song Q, Song Z, Mahmoud AM, Xu P, He C, Arpke RW, Kyba M, Shu G, Jiang Q, Jiang Y. Genetically prolonged beige fat in male mice confers long-lasting metabolic health. Nat Commun. 2023;14(1):2731. Epub 2023/05/12. doi: 10.1038/s41467-023-38471-z. PubMed PMID: 37169793; PMCID: PMC10175245.
2. Munoz MD, Zamudio A, McCann M, Gil V, Xu P, Liew CW. Activation of brown adipose tissue by a low-protein diet ameliorates hyperglycemia in a diabetic lipodystrophy mouse model. Sci Rep. 2023;13(1):11808. Epub 2023/07/22. doi: 10.1038/s41598-023-37482-6. PubMed PMID: 37479751; PMCID: PMC10362023.
3. Feng B, Liu H, Mishra I, Duerrschmid C, Gao P, Xu P, Wang C, He Y. Asprosin promotes feeding through SK channel-dependent activation of AgRP neurons. Sci Adv. 2023;9(8):eabq6718. Epub 2023/02/23. doi: 10.1126/sciadv.abq6718. PubMed PMID: 36812308; PMCID: PMC9946352.

2022

1. Yuan Y, Zhu C, Wang Y, Sun J, Feng J, Ma Z, Li P, Peng W, Yin C, Xu G, Xu P, Jiang Y, Jiang Q, Shu G. alpha-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling. Sci Adv. 2022;8(18):eabn2879. Epub 2022/05/05. doi: 10.1126/sciadv.abn2879. PubMed PMID: 35507647; PMCID: PMC9067931.